Celebrated actor and director Harold Ramis has died following complications from an autoimmune disease. He was 69.

More from the Chicago Tribune:

Ramis leaves behind a formidable body of work, with writing credits on such enduring comedies as “National Lampoon’s Animal House” (which upon its 1978 release catapulted the film career of John Belushi, with whom Ramis acted at Second City), “Stripes” (1981) and “Ghostbusters” (in which Ramis also co-starred) plus such directing efforts as “Caddyshack” (1980), “National Lampoon’s Vacation” (1983), “Groundhog Day” and “Analyze This.”

His death is not just a loss for the entertainment world, but also for the millions of fans he earned through decades of work.

https://twitter.com/ChefGrantSoto/status/438002845644627968

https://twitter.com/stephenfry/status/438008971287625728

R.I.P.

Editor’s note: This post has been updated with additional tweets.

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