Heartbreaking news this morning: A fire raced through a nightclub in Santa Maria, Brazil, after a reported pyrotechnic display, killing hundreds.

https://twitter.com/spanishNY/status/295538518015475712

https://twitter.com/spanishNY/status/295545036727271424

The death count has now climbed to 245.

Twitter users post video and photos from the horrifying and heartbreaking scene. (Warning: Disturbing photos and video.)

https://twitter.com/RadioNickBrasil/status/295551188873654274

https://twitter.com/bdomenech/status/295526221020819457

https://twitter.com/toninhocelestin/status/295537887531917313

https://twitter.com/Kent_999s/status/295527656592646145

The list of victims keeps growing.

https://twitter.com/spanishNY/status/295539170712109057

https://twitter.com/spanishNY/status/295539666210398208

https://twitter.com/shadowoffadream/status/295546897492488193

Calls for blood donations go out on Twitter.

“Help the victims of the fire at the Disco Kiss donating blood. Address is Av Pres. Vargas, 2291.”

And prayers go up from across the globe.

https://twitter.com/MKafelnikov/status/295517677726859265

https://twitter.com/Diguinhod10/status/295542615338803200

Two hashtags are being used to offer prayers and to relay information: #PrayForBrazil and #PrayForSantaMaria

Our thoughts and prayers continue to be with the victims and their families. Twitchy will continue to monitor this heartbreaking story and will update with further developments.